Description

Desacetyl Diltiazem Hydrochloride (50 Mg) is a key pharmaceutical intermediate and reference standard. This compound is of significant importance for research, development, and quality control processes in the pharmaceutical industry. It is primarily required by manufacturers and R&D laboratories involved in the synthesis and analysis of cardiovascular drugs, particularly calcium channel blockers.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of Diltiazem and its related active pharmaceutical ingredients (APIs).
• Reference Standard: Used for analytical method development, validation, and quality control testing in pharmaceutical laboratories.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research for cardiovascular therapeutics.
• Impurity Profiling: Serves as a known impurity standard to ensure the purity and safety of final drug products.
• Research & Development: Utilized in medicinal chemistry for the design and development of new calcium channel modulators.

Basic Information

Product Name	Desacetyl Diltiazem Hydrochloride (50 Mg)
CAS No.	23515-45-9
Molecular Formula	C21H27ClN2O4S • HCl
Molecular Weight	479.44 g/mol
Synonyms	Desacetyldiltiazem HCl; Diltiazem Impurity C; (2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride; N-Desacetyldiltiazem Hydrochloride; Diltiazem Related Compound C; 1,5-Benzothiazepin-4(5H)-one, 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-3-(acetyloxy)-2,3-dihydro-, hydrochloride, (2S-cis)-; (+)-cis-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride
EINECS	Contact for details

Quality Control

Our Desacetyl Diltiazem Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.