Description

Verapamil Hydrochloride CAS NO 23313-68-0 is a calcium channel blocker belonging to the phenylalkylamine class, widely recognized for its cardiovascular applications. This compound is critical for the development and production of pharmaceutical formulations targeting hypertension, angina, and certain arrhythmias. It is an essential active pharmaceutical ingredient (API) for manufacturers in the global pharmaceutical and life sciences industries, requiring consistent high purity and reliable supply chains.

Application

• Primary Active Pharmaceutical Ingredient (API) in antihypertensive medications.
• Key component in the formulation of antianginal drugs for chest pain management.
• Used in the production of antiarrhythmic agents for heart rhythm disorders.
• Critical raw material for pharmaceutical R&D and reference standard synthesis.
• Utilized in the development of controlled-release and combination drug formulations.
• Essential for the manufacturing of generic and branded cardiovascular drugs.

Basic Information

Product Name	Verapamil Hydrochloride
CAS No.	23313-68-0
Molecular Formula	C27H38N2O4 • HCl
Molecular Weight	491.07 g/mol
Synonyms	Verapamil HCl; (±)-Verapamil Hydrochloride; 5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile Hydrochloride; Iproveratril Hydrochloride; Cordilox; Isoptin; Calan; Anpec
EINECS	245-594-1

Quality Control

Our Verapamil Hydrochloride is manufactured under strict quality systems to meet the rigorous standards of the pharmaceutical industry. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other pharmacopeial methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with relevant pharmacopeial monographs (e.g., USP, EP, BP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Optical Rotation	-0.10° to +0.10° (c = 5 in methanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.