Description

Niludipine CAS NO 22609-73-0 is a high-purity pharmaceutical intermediate and research chemical belonging to the dihydropyridine class of calcium channel blockers. It is a critical building block in the synthesis and development of advanced cardiovascular therapeutics. This compound is essential for pharmaceutical R&D laboratories, API manufacturers, and academic institutions focused on cardiovascular disease research and drug discovery.

Application

• Pharmaceutical Active Ingredient (API) Synthesis: A key intermediate in the production of calcium channel blocker medications.
• Biomedical Research: Used as a reference standard and tool compound in pharmacological studies of vascular smooth muscle and cardiac function.
• Drug Discovery & Development: Serves as a lead compound or structural analog for developing new antihypertensive and antianginal agents.
• Analytical Chemistry: Employed as a certified reference material (CRM) for method development and quality control in analytical laboratories.
• Academic Studies: Utilized in university and institutional research to investigate calcium ion channel mechanisms and signal transduction pathways.

Basic Information

Item	Detail
Product Name	Niludipine
CAS No.	22609-73-0
Molecular Formula	C19H20N2O6
Molecular Weight	372.37 g/mol
Synonyms	Bay a 7168; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-(1-methylethyl) ester; Isopropyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; Bay-a-7168; Niludipin; Niludipina; Niludipinum
EINECS	Contact for details

Quality Control

Our Niludipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and pharmaceutical-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.