Description

Nifedipine CAS NO 21829-25-4 is a high-purity dihydropyridine calcium channel blocker, a critical active pharmaceutical ingredient (API) in cardiovascular therapeutics. Its primary value lies in its potent vasodilatory effects, which are essential for managing hypertension and angina pectoris. This compound is indispensable for pharmaceutical manufacturers and research institutions developing and producing antihypertensive and antianginal medications.

Application

• Primary Active Pharmaceutical Ingredient (API) in antihypertensive drug formulations.
• Core component in immediate-release and extended-release tablets for angina prophylaxis.
• Key intermediate in advanced pharmaceutical research for novel cardiovascular drugs.
• Reference standard in analytical laboratories for quality control and method validation.
• Starting material for the synthesis of other dihydropyridine derivatives.
• Used in clinical research studies investigating vascular smooth muscle relaxation.

Basic Information

Product Name	Nifedipine
CAS No.	21829-25-4
Molecular Formula	C17H18N2O6
Molecular Weight	346.34 g/mol
Synonyms	3,5-Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; Adalat; BAY a 1040; Nifedicor; Procardia; Fenihidin; Nifelat; Cordipin
EINECS	244-598-3

Quality Control

Our Nifedipine is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP, EP, and JP. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided to ensure full traceability and regulatory readiness for our pharmaceutical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and strictly light-sensitive nature, the container must be kept in original packaging until use and handled under conditions that minimize exposure to moisture and all light sources.

Specification

Item	Specification
Appearance	Yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time conforms to reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.