Description

Benazeprilat Benzyl Ester Analogue, Trifluoroacetic Acid Salt is a high-purity synthetic intermediate of significant importance in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis and structural modification of active pharmaceutical ingredients (APIs), particularly within the cardiovascular and metabolic therapeutic areas. It is primarily utilized by R&D chemists, process development scientists, and manufacturers in the pharmaceutical and biotechnology industries for creating novel drug candidates and optimizing synthetic pathways.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel Angiotensin-Converting Enzyme (ACE) inhibitors and related cardiovascular agents.
• Process Chemistry: Used in route scouting and scale-up studies for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Used as a tool compound in pharmacological studies to investigate enzyme inhibition mechanisms and metabolic pathways.
• Custom Synthesis: A starting material for the contract synthesis of specialized, non-commercially available analogues for targeted research programs.

Basic Information

Item	Details
Product Name	Benazeprilat Benzyl Ester Analogue, Trifluoroacetic Acid Salt
CAS No.	1356578-34-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Benazeprilat Benzyl Ester TFA Salt; Benazepril Related Compound; (3S)-3-[[(1S)-1-Carboxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic Acid Benzyl Ester Trifluoroacetate; ACE Inhibitor Intermediate; Benzazepine Derivative TFA Salt; Pharmaceutical Intermediate 1356578-34-1
EINECS	Contact for details

Quality Control

Our Benazeprilat Benzyl Ester Analogue, Trifluoroacetic Acid Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay, related substances, and residual solvents. We adhere to cGMP guidelines where applicable to support our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.