Description

Imidapril is a potent, long-acting angiotensin-converting enzyme (ACE) inhibitor used in the management of hypertension and heart failure. Its primary value lies in its ability to effectively lower blood pressure and reduce cardiac workload, offering a critical therapeutic option in cardiovascular medicine. This active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers and research institutions developing antihypertensive and cardioprotective formulations. Imidapril CAS NO 157085-07-9 is supplied under stringent quality controls to ensure efficacy and safety in final drug products.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for treating hypertension (high blood pressure).
• Cardiovascular Drug Formulations: Incorporated into tablets, capsules, and other solid oral dosage forms for chronic cardiovascular conditions.
• Heart Failure Management: Used in drug products aimed at improving survival and symptoms in patients with congestive heart failure.
• Clinical Research & Development: Serves as a reference standard and raw material in preclinical and clinical studies for new cardiovascular therapies.
• Generic Drug Manufacturing: A key component for companies producing bioequivalent versions of branded ACE inhibitor drugs.
• Combination Therapies: Potential use in fixed-dose combination drugs with other antihypertensive agents like diuretics or calcium channel blockers.

Basic Information

Product Name	Imidapril
CAS No.	157085-07-9
Molecular Formula	C20H27N3O6
Molecular Weight	405.45 g/mol
Synonyms	Imidapril Hydrochloride; (4S)-3-[(2S)-2-[[(1S)-1-Ethoxycarbonyl-3-phenylpropyl]amino]propanoyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid hydrochloride; TA-6366; Cilazaprilat methyl ester derivative; ACE Inhibitor TA-6366; Novarok; Tanatril
EINECS	Contact for details

Quality Control

Our Imidapril is manufactured and tested to meet the highest pharmacopeial standards, including USP and ICH Q7 guidelines for active pharmaceutical ingredients. Every batch undergoes rigorous analytical testing for identity, potency, purity, and impurity profiles using validated methods such as HPLC and NMR. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specification results and confirming compliance with agreed-upon standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants in the container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Meets USP <61> requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.