Description

Embusartan CAS NO 156001-18-2 is a potent and selective angiotensin II type 1 (AT1) receptor antagonist. This compound is a critical intermediate in the research and development of novel antihypertensive and cardiovascular therapeutic agents. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of advanced active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of sartans and other AT1 receptor antagonist drug candidates.
• Research & Development: Used in preclinical and clinical research to study the structure-activity relationship (SAR) of angiotensin receptor blockers.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Chemical Synthesis: Employed in organic synthesis for the construction of complex biphenyl-tetrazole derivative molecules.
• Academic Research: Utilized in university and institutional labs for pharmacological studies related to the renin-angiotensin system.

Basic Information

Product Name	Embusartan
CAS No.	156001-18-2
Molecular Formula	C25H20N6O3
Molecular Weight	452.46 g/mol
Synonyms	2-Butyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid; BIBR 277; BIBR-277; BIBR277; Embusartan (BIBR 277); 1H-Benzimidazole-7-carboxylic acid, 2-butyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
EINECS	Contact for details

Quality Control

Our Embusartan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.