Description

7-Propyl-6-((2'-(1H-Tetrazol-5-Yl)(1,1'-Biphenyl)-4-Yl)Methyl)-S-Triazolo(4,3-A)Pyrimidin-5-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting specific receptor pathways. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in cardiovascular and metabolic disease research.
• Angiotensin II Receptor Antagonist Research: Serves as a core structural component for developing sartan-class compounds due to the presence of the biphenyl-tetrazole moiety.
• Biochemical Research: Used as a reference standard or ligand in enzymatic and receptor-binding studies to understand biological pathways.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for complex molecule manufacturing within GMP environments.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.

Basic Information

Product Name	7-Propyl-6-((2'-(1H-Tetrazol-5-Yl)(1,1'-Biphenyl)-4-Yl)Methyl)-S-Triazolo(4,3-A)Pyrimidin-5-Ol
CAS No.	151327-13-8
Molecular Formula	C28H24N8O
Molecular Weight	488.55 g/mol
Synonyms	7-Propyl-6-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-[1,2,4]triazolo[4,3-a]pyrimidin-5-ol; 151327-13-8; Biphenyl-tetrazole triazolopyrimidine derivative; s-Triazolo[4,3-a]pyrimidin-5-ol, 7-propyl-6-((2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl)methyl)-; Losartan related compound; Angiotensin II antagonist intermediate
EINECS	Contact for details

Quality Control

Our 7-Propyl-6-((2'-(1H-Tetrazol-5-Yl)(1,1'-Biphenyl)-4-Yl)Methyl)-S-Triazolo(4,3-A)Pyrimidin-5-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and process development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.