Description

n-(2-(4-Morpholinyl)Ethyl)-5-Propyl-6-((2'-(1H-Tetrazol-5-Yl)(1,1'- Biphenyl)-4-Yl)Methyl) Pyrazolo(1,5-A)Pyrimidin-7-Amine is a high-purity, non-peptidic chemical compound with a complex heterocyclic structure, identified by CAS No. 151327-04-7. This molecule is of significant interest for its potential as a key intermediate or active pharmaceutical ingredient (API) in advanced therapeutic research. It is primarily sought by pharmaceutical R&D and fine chemical synthesis laboratories engaged in developing novel receptor-targeted therapies. Its structural features make it a valuable building block for medicinal chemistry programs.

Application

This specialized chemical serves as a critical component in several advanced research and development areas:

• Pharmaceutical Intermediate: Acts as a key synthetic precursor in the development of novel angiotensin II receptor antagonists and related cardiovascular drugs.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Employed in in vitro assays to study receptor-ligand interactions and cellular signaling pathways.
• Fine Chemical Synthesis: Serves as a complex intermediate for the custom synthesis of other high-value, specialized organic molecules.
• Contract Research & Development (CRO/CMO): Supplied to organizations conducting proprietary research on hypertension, heart failure, and related therapeutic areas.

Basic Information

Product Name	n-(2-(4-Morpholinyl)Ethyl)-5-Propyl-6-((2'-(1H-Tetrazol-5-Yl)(1,1'- Biphenyl)-4-Yl)Methyl) Pyrazolo(1,5-A)Pyrimidin-7-Amine
CAS No.	151327-04-7
Molecular Formula	C₃₀H₃₄N₁₀O
Molecular Weight	550.66 g/mol
Synonyms	Valsartan Impurity; Valsartan Related Compound; 5-Propyl-6-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-N-[2-(4-morpholinyl)ethyl]pyrazolo[1,5-a]pyrimidin-7-amine; L-Valine, N-(1-oxopentyl)-, (2S)-, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]benzimidazole-7-carboxylate (non-preferred); BMS-180560-05; UNII-80M03YXJ7I
EINECS	Contact for details

Quality Control

Our production of n-(2-(4-Morpholinyl)Ethyl)-5-Propyl-6-((2'-(1H-Tetrazol-5-Yl)(1,1'- Biphenyl)-4-Yl)Methyl) Pyrazolo(1,5-A)Pyrimidin-7-Amine adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch is analyzed using advanced chromatographic and spectroscopic techniques to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results are provided with every shipment. We support compliance with ICH guidelines for impurities and can tailor specifications to meet client-specific pharmacopeial or internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under conditions of low humidity to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.