Description

Levamlodipine Besylate CAS NO 150566-71-5 is the S-enantiomer of the dihydropyridine calcium channel blocker amlodipine, formulated as its besylate salt. This high-purity active pharmaceutical ingredient (API) is critical for developing single-enantiomer cardiovascular therapeutics, offering targeted pharmacological activity with potentially improved efficacy and reduced side-effect profiles. It is essential for pharmaceutical manufacturers and R&D organizations focused on innovating next-generation antihypertensive and antianginal medications.

Application

• Pharmaceutical API: Primary active ingredient in the formulation of single-enantiomer antihypertensive drugs.
• Cardiovascular Research: Key reference standard and investigational compound in preclinical and clinical studies for hypertension and angina.
• Drug Development: Used in the development of new dosage forms, including controlled-release tablets and combination therapies.
• Analytical Standard: Serves as a certified reference material (CRM) for quality control and method validation in analytical laboratories.
• Process Chemistry: Intermediate in the sophisticated synthesis of advanced chiral pharmaceutical compounds.

Basic Information

Product Name	Levamlodipine Besylate
CAS No.	150566-71-5
Molecular Formula	C26H31ClN2O8S
Molecular Weight	567.05 g/mol
Synonyms	(S)-Amlodipine Besylate; (S)-Amlodipine Benzenesulfonate; Levamlodipine Benzenesulfonate; S(-)-Amlodipine Besylate; (4S)-2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-ethyl 5-methyl ester benzenesulfonate; Amlong-S; S-Amlodipine; EsCordi Cor
EINECS	Contact for details

Quality Control

Our Levamlodipine Besylate is manufactured under strict quality management systems, targeting purity levels suitable for pharmaceutical applications. Each batch is tested against rigorous in-house specifications to ensure identity, potency, and purity. A comprehensive Certificate of Analysis (COA) detailing results for assay, enantiomeric purity, related substances, residual solvents, and microbiological limits is provided with every shipment. We adhere to cGMP principles to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Enantiomeric Purity (Chiral HPLC)	≥ 99.5%
Related Substances (HPLC)	Total impurities ≤ 0.5% Any single impurity ≤ 0.2%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.