Description

Saprisartan Potassium CAS NO 146613-90-3 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) belonging to the angiotensin II receptor antagonist (ARB) class. This compound is critical for the research, development, and manufacturing of advanced cardiovascular therapeutics targeting hypertension. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic research institutions engaged in drug discovery and production.

Application

• Active Pharmaceutical Ingredient (API) in the synthesis of antihypertensive medications.
• Pharmaceutical Intermediate for the production of Sartan-class cardiovascular drugs.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Biochemical Research for studying angiotensin II receptor mechanisms and pathways.
• Formulation Development for creating novel drug delivery systems and dosage forms.
• Process Chemistry and scale-up studies for commercial manufacturing.

Basic Information

Product Name	Saprisartan Potassium
CAS No.	146613-90-3
Molecular Formula	C27H29KN6O3
Molecular Weight	524.66 g/mol
Synonyms	Saprisartan K; Potassium Saprisartan; BIBR-277-SE Potassium Salt; 2-Butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol potassium salt; 1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, potassium salt (1:1); BIBR 277 SE Potassium; Saprisartan Potassium Salt
EINECS	Contact for details

Quality Control

Our Saprisartan Potassium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with client specifications and relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤1.5%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.