Description

Telmisartan CAS NO 144701-48-4 is a potent and highly selective angiotensin II receptor blocker (ARB) used as an active pharmaceutical ingredient (API). This compound is critical for the formulation of antihypertensive medications, offering effective blood pressure control and cardiovascular protection. It is primarily required by pharmaceutical manufacturers and research institutions engaged in developing and producing advanced cardiovascular therapies.

Application

• Primary Pharmaceutical Ingredient: Core API in the manufacture of antihypertensive tablets and combination drugs for treating high blood pressure (hypertension).
• Cardiovascular Risk Reduction: Used in formulations aimed at reducing the risk of major cardiovascular events such as heart attack and stroke.
• Generic Drug Production: Essential for the synthesis of generic versions of branded telmisartan medications for global markets.
• Pharmaceutical Research & Development: Serves as a reference standard and key intermediate in preclinical and clinical research for new cardiovascular drug candidates.
• Fixed-Dose Combination Drugs: Combined with other APIs like hydrochlorothiazide or amlodipine to create synergistic treatments for hypertension.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for commercial-scale pharmaceutical production.

Basic Information

Product Name	Telmisartan
CAS No.	144701-48-4
Molecular Formula	C33H30N4O2
Molecular Weight	514.62 g/mol
Synonyms	4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid; BIBR 277; BIBR-277SE; Micardis (Brand Name); Pritor (Brand Name); Kinzalmono (Brand Name); Telmisartanum; Telmisartanum
EINECS	Contact for details

Quality Control

Our Telmisartan API is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure compliance with major pharmacopoeial standards such as USP, EP, and JP. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to meet the stringent requirements of pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.