Description

Olmesartan CAS NO 144689-78-1 is a potent and selective angiotensin II receptor blocker (ARB) used as an active pharmaceutical ingredient (API). It is a critical component in the formulation of antihypertensive medications, effectively managing high blood pressure by blocking the action of angiotensin II. This compound is essential for pharmaceutical manufacturers and research institutions developing cardiovascular therapies, including combination drugs.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the manufacture of antihypertensive drugs.
• Formulation of oral solid dosage forms such as tablets and capsules containing Olmesartan medoxomil.
• Research and development of novel cardiovascular drug combinations and delivery systems.
• Production of generic pharmaceutical products for the global market.
• Use in clinical research and pharmacological studies.
• Reference standard in analytical laboratories for quality control and method development.

Basic Information

Product Name	Olmesartan
CAS No.	144689-78-1
Molecular Formula	C₂₉H₃₀N₆O₆
Molecular Weight	558.59 g/mol
Synonyms	Olmesartan Medoxomil; Benicar (Trade Name); RN-102807; CS-866; 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid, 5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester; 2,3-Dihydroxy-2-buten-1,4-diyl bis(4-[[2-propyl-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazol-5-yl]carbonyl]benzoate); (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]imidazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our Olmesartan API is produced under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing parameters such as assay, related substances, and residual solvents. We support compliance with major pharmacopeial standards, including USP and ICH Q3A/B guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.15% Total impurities: NMT 1.0%
Water (KF Titration)	NMT 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	NMT 20 ppm
Sulfated Ash	NMT 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.