Description

Olmesartan Medoxomil is a potent and selective angiotensin II receptor blocker (ARB) used as an antihypertensive agent. This high-purity active pharmaceutical ingredient (API) is critical for the reliable and consistent manufacturing of finished dosage forms. It is primarily required by pharmaceutical companies and research institutions engaged in the development and production of cardiovascular medications.

Application

• Primary Pharmaceutical Ingredient: Core API in the formulation of oral solid dosage forms (e.g., tablets, capsules) for the treatment of hypertension (high blood pressure).
• Combination Drug Therapy: Used in fixed-dose combination products with other antihypertensives like amlodipine or hydrochlorothiazide for enhanced therapeutic effect.
• Pharmaceutical R&D: Serves as a reference standard and key intermediate in analytical method development, stability studies, and new drug formulation research.
• Generic Drug Manufacturing: Essential for producers of generic olmesartan medoxomil tablets following patent expirations, ensuring bioequivalence to brand-name drugs.
• Clinical Trial Material: Supplied as GMP-grade material for use in pre-clinical and clinical studies to establish safety and efficacy profiles.

Basic Information

Product Name	Olmesartan Medoxomil
CAS No.	144689-63-4
Molecular Formula	C29H30N6O6
Molecular Weight	558.59 g/mol
Synonyms	Olmesartan Medoxomil; Olmesartan Medoxomilum; Benicar (Trade Name); RN-132798; CS-866; (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our Olmesartan Medoxomil is manufactured under strict quality management systems. It is typically supplied to meet or exceed major pharmacopeial standards such as USP and EP. Every batch undergoes comprehensive analytical testing including identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.