Description

Irbesartan is a potent and selective angiotensin II receptor antagonist (ARB) used primarily as an active pharmaceutical ingredient (API). It is a critical compound in the global pharmaceutical supply chain for the formulation of antihypertensive and cardioprotective medications. This high-purity substance is essential for manufacturers in the pharmaceutical industry producing tablets and other dosage forms to treat high blood pressure and diabetic nephropathy.

Application

• Pharmaceutical API: Primary use as the active ingredient in antihypertensive drug formulations.
• Hypertension Treatment: Manufacture of tablets and combination drugs for managing high blood pressure.
• Diabetic Nephropathy Therapy: Production of medications to slow kidney disease progression in patients with type 2 diabetes and hypertension.
• Cardiovascular Protection: Used in formulations aimed at reducing cardiovascular risk in hypertensive patients.
• Generic Drug Manufacturing: Sourcing for the production of generic versions of branded ARB medications.
• Clinical Research: Serves as a reference standard or raw material in pharmacological studies and new drug development.

Basic Information

Product Name	Irbesartan
CAS No.	141745-36-0
Molecular Formula	C25H28N6O
Molecular Weight	428.53 g/mol
Synonyms	2-Butyl-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1,3-diazaspiro[4.4]non-1-en-4-one; BMS-186295; SR 47436; Avapro® (Brand Name); Karvea® (Brand Name); Approvel® (Brand Name); Irovel® (Brand Name)
EINECS	Contact for details

Quality Control

Our Irbesartan is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Every batch undergoes comprehensive analytical testing including identification, assay, impurity profiling, and residual solvent analysis to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) documenting all test results is provided with each shipment to guarantee traceability and quality assurance for our B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.2% Total impurities: ≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.