Description

Candesartan is a potent and selective angiotensin II receptor blocker (ARB) used as an active pharmaceutical ingredient (API). This compound is critical for the formulation of antihypertensive medications, effectively managing high blood pressure and related cardiovascular conditions. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of cardiovascular drugs and novel therapeutic formulations.

Application

• Pharmaceutical API: Primary use as the active ingredient in finished dosage forms for the treatment of hypertension (high blood pressure).
• Cardiovascular Drug Formulations: Used in the manufacture of tablets, capsules, and other oral solid dosage forms.
• Combination Therapies: Incorporated into fixed-dose combination drugs with other antihypertensive agents like hydrochlorothiazide.
• Clinical Research: Serves as a reference standard and key material in pharmacokinetic, pharmacodynamic, and bioequivalence studies.
• Generic Drug Production: Essential for manufacturers producing generic versions of branded candesartan-based medications.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for managing hypertension in animals.

Basic Information

Product Name	Candesartan
CAS No.	139481-59-7
Molecular Formula	C24H20N6O3
Molecular Weight	440.45 g/mol
Synonyms	Candesartan Cilexetil Impurity; (±)-1-Hydroxyethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylate; TCV-116; CV-11974; Blopress; Atacand; Amias; Candesartan Cilexetil Metabolite; 1-Hydroxyethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate
EINECS	Contact for details

Quality Control

Our Candesartan is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) are provided with each batch, detailing specifications for identity, purity, and impurities. We can support compliance with various pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The container should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	NMT 2.0%
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.