Description

Alanine Valsartan is a high-purity, non-peptide angiotensin II receptor antagonist (ARB) used as a key pharmaceutical intermediate. Its primary value lies in the synthesis of Valsartan, a leading active pharmaceutical ingredient (API) for treating hypertension and heart failure. This compound is essential for manufacturers in the global pharmaceutical industry requiring reliable, high-quality building blocks for API production. The material is supplied with full traceability and documentation to support stringent regulatory requirements.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the multi-step synthesis of the antihypertensive drug Valsartan.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a key building block for GMP-compliant production of Valsartan API batches.
• Research & Development: Used in pharmaceutical R&D for developing new sartan-based therapies or novel drug delivery systems.
• Process Chemistry & Scale-Up: Employed in process optimization and pilot-scale studies for efficient API manufacturing.
• Reference Standard: Can be utilized as a high-purity analytical reference standard for quality control and method validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for commercial API production.

Basic Information

Product Name	Alanine Valsartan
CAS No.	137862-57-8
Molecular Formula	C₂₄H₂₉N₅O₃
Molecular Weight	435.52 g/mol
Synonyms	L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, (S)-; (S)-N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]valine; Valsartan Alanine Intermediate; Valsartan Impurity; Valsartan Related Compound A; SC-52458; ZD-7155 intermediate
EINECS	Contact for details

Quality Control

Our Alanine Valsartan is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and control of specified impurities. We provide full traceability and support regulatory filings with detailed documentation. Certificates of Analysis (COA) are available upon request, confirming compliance with in-house specifications tailored for pharmaceutical intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to protect from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.