Description

Azilsartan is a potent and selective angiotensin II receptor blocker (ARB) used as an active pharmaceutical ingredient (API). It is a key therapeutic agent in the management of hypertension, offering effective blood pressure control. This high-purity compound is essential for pharmaceutical manufacturers developing finished dosage forms, such as tablets, for the global cardiovascular drug market. Azilsartan CAS NO 136285-68-2 is supplied under stringent quality controls to ensure compliance with international pharmacopeial standards.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in antihypertensive medications.
• Formulation into solid oral dosage forms, primarily tablets (e.g., Azilsartan medoxomil).
• Research and development of novel cardiovascular drug combinations and fixed-dose combinations.
• Use in pharmaceutical reference standards for quality control and analytical testing.
• Preclinical and clinical pharmacology studies related to the renin-angiotensin system.
• Development of generic drug formulations following patent expirations.

Basic Information

Product Name	Azilsartan
CAS No.	136285-68-2
Molecular Formula	C25H20N4O5
Molecular Weight	456.45 g/mol
Synonyms	TAK-536; Azilsartan free acid; 2-Ethoxy-1-[[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid; (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-1-[[2'-(5-oxo-4H-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate (Azilsartan medoxomil precursor); BMS-757095; UNII-4X7P5P6OQR
EINECS	Contact for details

Quality Control

Our Azilsartan is manufactured under strict quality management systems, targeting compliance with ICH Q7 guidelines and relevant pharmacopeial monographs (e.g., USP, EP). Every batch undergoes comprehensive analytical testing, including identity, purity, and impurity profile determination via advanced techniques like HPLC. A Certificate of Analysis (COA) documenting all release specifications is provided with each shipment to ensure full traceability and regulatory support for our clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual unknown impurity ≤ 0.10% Total impurities ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.