Description

Alatrioprilat is a high-purity, non-peptide angiotensin-converting enzyme (ACE) inhibitor, a key intermediate in the synthesis of advanced pharmaceutical compounds. Its primary value lies in its potent and specific biological activity, making it a critical building block for cardiovascular research and drug development. This compound is essential for pharmaceutical manufacturers and R&D laboratories focused on creating next-generation antihypertensive and cardioprotective agents.

Application

• Pharmaceutical Intermediate: Primary use as a critical synthetic precursor in the manufacture of active pharmaceutical ingredients (APIs) for ACE inhibitor drugs.
• Cardiovascular Research: Used in biochemical and pharmacological studies to investigate the renin-angiotensin system and mechanisms of blood pressure regulation.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Preclinical Development: Employed in the discovery and optimization stages of new therapeutic candidates targeting hypertension and heart failure.
• Academic Research: Utilized in university and institutional labs for studying enzyme kinetics and inhibitor design.

Basic Information

Product Name	Alatrioprilat
CAS No.	135038-59-4
Molecular Formula	C20H28N2O5S
Molecular Weight	408.51 g/mol
Synonyms	Alatrioprilat; (S)-1-[6-Amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline; Alatriopril Diacid; RU 44403; SQ 32,829; 3-(1-Carboxy-3-phenylpropyl)amino-2-oxo-4-phenylbutylphosphinic acid; Ace Inhibitor Alatrioprilat
EINECS	Contact for details

Quality Control

Our Alatrioprilat is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) are provided with every shipment, detailing full compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.