Description

2-[4-(4-Benzhydrylpiperazin-1-Yl)Phenyl]Ethyl Methyl 2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3,5-Dicarboxylate is a high-purity, complex organic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its intricate molecular structure, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly within the cardiovascular and neurological domains. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel dihydropyridine-class calcium channel blockers and other potential therapeutic molecules.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Reference Standard: Serves as a high-purity analytical standard for method development, quality control, and regulatory submissions in pharmaceutical analysis.
• Process Chemistry Development: Employed in route scouting and process optimization for the efficient and scalable manufacturing of target APIs.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry, reaction mechanisms, and the development of new synthetic methodologies.
• Custom Synthesis Building Block: Provides a versatile starting point for contract research organizations (CROs) and CDMOs working on client-specific molecular targets.

Basic Information

Product Name	2-[4-(4-Benzhydrylpiperazin-1-Yl)Phenyl]Ethyl Methyl 2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3,5-Dicarboxylate
CAS No.	134054-36-7
Molecular Formula	C42H44N4O6
Molecular Weight	700.83 g/mol
Synonyms	Methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate, 2-[4-[4-(diphenylmethyl)-1-piperazinyl]phenyl]ethyl ester; 2-[4-(4-Benzhydryl-1-piperazinyl)phenyl]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate; 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-[2-[4-[4-(diphenylmethyl)-1-piperazinyl]phenyl]ethyl] methyl ester; CAS 134054-36-7; Benzhydrylpiperazine Dihydropyridine Derivative; Nitrophenyl DHP Ester Intermediate.
EINECS	Contact for details

Quality Control

Our 2-[4-(4-Benzhydrylpiperazin-1-Yl)Phenyl]Ethyl Methyl 2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3,5-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and assay, NMR and IR for structural confirmation, and tests for residual solvents and related substances to ensure it meets exacting R&D and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent product degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.