Description

Vatanidipine Hydrochloride is a high-purity active pharmaceutical ingredient (API) belonging to the dihydropyridine class of calcium channel blockers. This compound is critical for pharmaceutical research and development, particularly in the formulation of cardiovascular therapeutics. It is primarily utilized by pharmaceutical manufacturers, R&D laboratories, and academic institutions engaged in drug discovery and synthesis.

Application

• Pharmaceutical API: Primary active ingredient in the development and production of antihypertensive medications.
• Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method validation in pharmaceutical testing.
• Biochemical Research: Serves as a key reagent in pharmacological studies investigating calcium channel modulation and vascular smooth muscle function.
• Process Development: Employed in the scale-up and optimization of synthetic routes for commercial drug manufacturing.
• Formulation Studies: Used in pre-formulation and stability testing for developing various dosage forms such as tablets or capsules.

Basic Information

Product Name	Vatanidipine Hydrochloride
CAS No.	133743-71-2
Molecular Formula	C₂₇H₃₃N₃O₆ • HCl
Molecular Weight	524.03 g/mol
Synonyms	Vatanidipine HCl; CCB-147; (±)-Vatanidipine Hydrochloride; 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3-[2-[4-(diphenylmethyl)-1-piperazinyl]ethyl] 5-methyl ester, hydrochloride; (RS)-Vatanidipine Hydrochloride; Vatanidipine Monohydrochloride
EINECS	Contact for details

Quality Control

Our Vatanidipine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications for pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.