Description

Benazepril is a potent, long-acting angiotensin-converting enzyme (ACE) inhibitor used primarily as an active pharmaceutical ingredient (API). Its core value lies in its efficacy for managing hypertension and heart failure, offering a critical therapeutic option for cardiovascular health. This compound is essential for pharmaceutical manufacturers developing finished dosage forms, such as tablets and capsules, for the global healthcare market.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in antihypertensive medications.
• Formulation of solid oral dosage forms, including tablets and capsules, for the treatment of high blood pressure.
• Clinical use in the management of congestive heart failure to improve patient outcomes.
• Component in combination drug therapies for enhanced cardiovascular treatment regimens.
• Use in pharmaceutical research and development for new therapeutic applications.
• Reference standard in analytical and quality control laboratories for method validation and testing.

Basic Information

Product Name	Benazepril
CAS No.	131064-75-0
Molecular Formula	C24H28N2O5•HCl
Molecular Weight	460.95 g/mol (Hydrochloride salt)
Synonyms	Benazepril Hydrochloride; CGS-14824A; CGS 14824; CGS14824A; (3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid hydrochloride; Lotensin (Brand Name); Briem (Brand Name); Zinadril (Brand Name)
EINECS	Contact for details

Quality Control

Our Benazepril is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP, EP, and ICH Q7 guidelines for active substances. Every batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and quality assurance for our B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.