Description

Idrapril is a high-purity active pharmaceutical ingredient (API) primarily recognized for its role as an angiotensin-converting enzyme (ACE) inhibitor. This compound is critical for the development and production of cardiovascular medications, offering a targeted mechanism for blood pressure regulation. It is essential for pharmaceutical manufacturers and research institutions focused on antihypertensive therapies and related cardiovascular disease research.

Application

• Pharmaceutical API: Primary active ingredient in the formulation of prescription antihypertensive drugs.
• Cardiovascular Research: Key reference standard and biochemical tool for studying ACE inhibition pathways in preclinical studies.
• Generic Drug Manufacturing: Serves as the core component for producing generic versions of ACE inhibitor medications.
• Dosage Form Development: Used in R&D for creating various solid oral dosage forms such as tablets and capsules.
• Analytical Standard: High-purity grade used as a reference standard in quality control laboratories for HPLC, LC-MS, and spectroscopic assays.

Basic Information

Item	Detail
Product Name	Idrapril
CAS No.	127420-24-0
Molecular Formula	C20H28N2O5S
Molecular Weight	408.51 g/mol
Synonyms	Idrapril; (S)-1-[6-Amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline; CGS 16617; CGS-16617; UNII-7BZQ0U6Q8I; L-Proline, 1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-, (S)-
EINECS	Contact for details

Quality Control

Our Idrapril is manufactured under strict quality management systems, ensuring it meets the rigorous standards required for pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP, ICH Q7 guidelines, and relevant pharmacopoeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.