Description

Sagandipine CAS NO 126294-30-2 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) belonging to the dihydropyridine class of calcium channel blockers. It is a critical building block in the research and synthesis of advanced cardiovascular therapeutics designed to manage hypertension and angina. This compound is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions focused on developing and producing next-generation cardiovascular drugs.

Application

• Pharmaceutical API Synthesis: Primary use as an active pharmaceutical ingredient in the manufacture of calcium channel blocker medications.
• Cardiovascular Drug Research: Key intermediate in the R&D of new antihypertensive and antianginal drug candidates.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical testing laboratories.
• Process Chemistry: Used in scale-up and optimization studies for the commercial production of dihydropyridine-based drugs.
• Academic & Institutional Research: Employed in pharmacological studies to investigate mechanisms of vascular smooth muscle relaxation.

Basic Information

Product Name	Sagandipine
CAS No.	126294-30-2
Molecular Formula	C19H18N2O6
Molecular Weight	370.36 g/mol
Synonyms	Sagandipine; 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-(2-methoxyethyl) 5-methyl ester; 3-(2-Methoxyethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; Sagandipinum; UNII-7K5FKL8B4S; Sagandipin; 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-(2-methoxyethyl) 5-methyl ester
EINECS	Contact for details

Quality Control

Our Sagandipine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and support current Good Manufacturing Practice (cGMP) standards for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this light-sensitive compound.

Specification

Item	Specification
Appearance	Yellow to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.