Description

Remikiren is a potent and selective renin inhibitor, representing a significant class of compounds for cardiovascular research. This high-purity compound is essential for pharmaceutical development and biochemical studies targeting the renin-angiotensin system. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel antihypertensive agents and metabolic pathway analysis.

Application

• Pharmaceutical R&D: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel antihypertensive drugs.
• Biochemical Research: Used as a specific tool compound to study the renin-angiotensin-aldosterone system (RAAS) and its role in blood pressure regulation and cardiovascular diseases.
• Mechanism of Action Studies: Employed in in vitro and in vivo models to investigate the pharmacology and efficacy of renin inhibition.
• Analytical Standard: Functions as a certified reference material for quality control and assay development in pharmaceutical manufacturing.
• Preclinical Development: Utilized in pharmacokinetic, pharmacodynamic, and toxicology studies during early drug discovery phases.

Basic Information

Product Name	Remikiren
CAS No.	126222-34-2
Molecular Formula	C33H41N3O4
Molecular Weight	543.70 g/mol
Synonyms	Ro 42-5892; (2S,4S,5S)-5-[(t-Butoxycarbonyl)amino]-4-hydroxy-6-phenyl-2-(2-methylpropyl)hexanoyl-L-histidyl-L-[(3aS,7aS)-octahydro-1H-indol-2-yl]alanine amide; Remikirenum; Remikireno; Remikirenum; Ro-42-5892; Ro 425892
EINECS	Contact for details

Quality Control

Our Remikiren is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.