Description

3-Methyl 5-Piperidin-3-Yl 2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3,5-Dicarboxylate Hcl is a high-purity, chemically defined dihydropyridine derivative, primarily utilized as a critical pharmaceutical intermediate in advanced synthesis. Its value lies in its specific molecular architecture, which makes it a key building block for developing active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is essential for research organizations, fine chemical manufacturers, and pharmaceutical companies engaged in the development of novel cardiovascular and neurological agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex dihydropyridine-based Active Pharmaceutical Ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates, particularly for calcium channel modulation.
• Fine Chemical Synthesis: Serves as a specialized building block for creating complex organic molecules in custom synthesis projects.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Item	Details
Product Name	3-Methyl 5-Piperidin-3-Yl 2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3,5-Dicarboxylate Hcl
CAS No.	121145-30-0
Molecular Formula	C24H29N3O6 • HCl
Molecular Weight	507.97 g/mol
Synonyms	1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl 5-(3-piperidinyl) ester hydrochloride; 3-Methyl 5-(3-piperidinyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate hydrochloride; Dihydropyridine derivative HCl salt; CAS 121145-30-0; 4-(3-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-methyl ester 5-(3-piperidyl) ester hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Methyl 5-Piperidin-3-Yl 2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3,5-Dicarboxylate Hcl is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.