Description

Manidipine is a potent and selective dihydropyridine calcium channel blocker used primarily as an antihypertensive agent. Its high selectivity for vascular smooth muscle makes it a valuable active pharmaceutical ingredient (API) for developing cardiovascular medications. This compound is essential for pharmaceutical manufacturers and research institutions focused on creating treatments for hypertension and related cardiovascular disorders. We supply high-purity Manidipine CAS NO 120092-68-4 to support global drug development and production.

Application

• Pharmaceutical API: Primary use as the active ingredient in antihypertensive and antianginal drug formulations.
• Cardiovascular Research: A key reference standard and tool compound for studying calcium channel mechanisms and vascular physiology.
• Generic Drug Manufacturing: Sourcing for the production of generic versions of calcium channel blocker medications.
• Preclinical & Clinical Development: Used in the development and testing of new cardiovascular therapies.
• Analytical Standard: Serves as a high-purity standard for quality control and analytical method development (HPLC, GC, etc.).
• Chemical Intermediate: Potential use in the synthesis of more complex pharmaceutical molecules or derivatives.

Basic Information

Product Name	Manidipine
CAS No.	120092-68-4
Molecular Formula	C35H38N4O6
Molecular Weight	610.70 g/mol
Synonyms	Manidipine; Manidipine Hydrochloride; CV-4093; 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester; Falican; Calslot; Manyper; Iperten; (±)-Manidipine
EINECS	Contact for details

Quality Control

Our Manidipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide full traceability and support regulatory filings with detailed documentation. Certificates of Analysis (COA) confirming identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.