Description

Dexniguldipine CAS NO 120054-86-6 is a potent and selective calcium channel antagonist belonging to the dihydropyridine class. This compound is of significant interest in pharmaceutical research and development due to its potential as a biochemical tool for studying L-type calcium channels and related cellular processes. It is primarily utilized by research institutions, pharmaceutical companies, and contract research organizations (CROs) engaged in cardiovascular research, neuropharmacology, and drug discovery programs.

Application

• Biochemical Research: Used as a reference standard and selective inhibitor in studies of voltage-gated L-type calcium channels.
• Cardiovascular Pharmacology: Investigated for its effects on vascular smooth muscle and cardiac tissue in preclinical models.
• Neuropharmacology: Employed in research exploring calcium channel function in neuronal signaling and related disorders.
• Drug Discovery & Development: Serves as a lead compound or pharmacophore model for designing new calcium channel modulators.
• Academic Research: Utilized in university and institutional labs for fundamental studies in cell biology and physiology.
• Contract Research: Supplied to CROs conducting specialized client-sponsored research requiring high-purity reference materials.

Basic Information

Product Name	Dexniguldipine
CAS No.	120054-86-6
Molecular Formula	C26H28N2O6
Molecular Weight	464.51 g/mol
Synonyms	Dexniguldipine; B 859-35; B859-35; B 859-35; B85935; (R)-(-)-Niguldipine; (R)-Niguldipine; (-)-Niguldipine; (R)-(-)-B859-35
EINECS	Contact for details

Quality Control

Our Dexniguldipine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity determination by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications for your records and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.