Description

Elgodipine is a high-purity pharmaceutical intermediate and active ingredient, identified by CAS NO 119413-55-7. It is a critical building block in the synthesis of advanced calcium channel blockers, offering precise chemical functionality for targeted therapeutic development. This compound is essential for research institutions and pharmaceutical manufacturers engaged in cardiovascular drug discovery, formulation, and process development.

Application

• Pharmaceutical Active Ingredient (API): Primary use as a key intermediate in the synthesis of dihydropyridine-class calcium channel blockers.
• Cardiovascular Drug Research: Essential for R&D of new antihypertensive and antianginal medications targeting L-type calcium channels.
• Process Chemistry & Scale-up: Used in the development and optimization of synthetic routes for bulk API manufacturing.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical production.
• Academic & Institutional Research: Utilized in pharmacological studies to investigate mechanisms of vascular smooth muscle relaxation.

Basic Information

Product Name	Elgodipine
CAS No.	119413-55-7
Molecular Formula	C19H20N2O6
Molecular Weight	372.38 g/mol
Synonyms	Elgodipine; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-(1-methylethyl) ester; Isopropyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; 4-(3-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-methyl 5-(1-methylethyl) ester
EINECS	Contact for details

Quality Control

Our Elgodipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) are provided with every shipment, and we support compliance with cGMP, ICH Q7, and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.