Description

Benidipine is a potent and highly selective dihydropyridine-class calcium channel blocker (CCB) primarily used in pharmaceutical research and development. Its core value lies in its long-lasting action and vascular selectivity, making it a key compound for studying cardiovascular therapeutics. This product is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions focused on hypertension, angina, and renal protection research. Benidipine CAS NO 119065-60-0 is supplied under strict quality control to ensure consistency for critical applications.

Application

• Pharmaceutical Active Ingredient (API): Serves as the core active component in the formulation of antihypertensive and antianginal medications.
• Reference Standard: Used as a high-purity standard in analytical laboratories for quality control (QC) and quality assurance (QA) of drug products.
• Biomedical Research: A vital tool for in vitro and in vivo studies investigating calcium channel physiology, vascular smooth muscle relaxation, and cardiovascular disease mechanisms.
• Process Development: Employed in the development and optimization of synthetic routes for calcium channel blockers within process chemistry.
• Formulation Studies: Used in pre-formulation and formulation research to develop stable and effective dosage forms such as tablets.

Basic Information

Product Name	Benidipine
CAS No.	119065-60-0
Molecular Formula	C28H31N3O6
Molecular Weight	505.57 g/mol
Synonyms	(±)-Benidipine; KW-3049; FRC-8653; 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-(1-benzyl-3-piperidinyl) ester 5-methyl ester; Coniel; 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-(1-benzyl-3-piperidinyl) ester 5-methyl ester
EINECS	Contact for details

Quality Control

Our Benidipine is manufactured and tested to meet stringent pharmaceutical-grade standards. Every batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and IR spectroscopy. We provide full traceability and support regulatory submissions with comprehensive documentation. Certificates of Analysis (COA) detailing all test results are available upon request to ensure compliance with your specific quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.