Description

Benidipine is a potent and highly selective dihydropyridine calcium channel blocker used primarily in pharmaceutical research and development. Its value lies in its long-lasting action and specific affinity for vascular L-type calcium channels, making it a critical compound for studying cardiovascular therapeutics. This product is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions focused on developing treatments for hypertension and angina.

Application

• Pharmaceutical Active Ingredient (API): Serves as the core active component in the formulation of antihypertensive and antianginal medications.
• Reference Standard: Used as a high-purity standard in analytical laboratories for quality control (QC) and quality assurance (QA) of drug products.
• Biochemical Research: A vital tool for pharmacological studies investigating calcium channel function, vascular smooth muscle contraction, and cardiovascular disease mechanisms.
• Preclinical Development: Employed in the research and development phase for new drug candidates targeting cardiovascular conditions.
• Metabolite Studies: Used in the synthesis and analysis of benidipine metabolites for pharmacokinetic and metabolic pathway research.

Basic Information

Item	Detail
Product Name	Benidipine
CAS No.	119009-44-8
Molecular Formula	C28H31N3O6
Molecular Weight	505.57 g/mol
Synonyms	(±)-Benidipine; FRC-8653; KW-3049; 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[1-(diphenylmethyl)-3-azetidinyl] 5-methyl ester; Coniel; 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[1-(benzhydryl)-3-azetidinyl] ester 5-methyl ester
EINECS	Contact for details

Quality Control

Our Benidipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other validated methods, to ensure it meets stringent specifications for pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.