Description

2,6-Dimethyl-3,5-Bis(2'-Propoxyethoxycarbonyl)-4-(2''-Difluoromethoxyphenyl)-1,4-Dihydropyridine is a sophisticated, high-purity dihydropyridine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmaceutical intermediate or active pharmaceutical ingredient (API) precursor, valued for its specific structural features that modulate biological activity. It is primarily utilized by R&D laboratories and pharmaceutical manufacturers engaged in the synthesis of novel cardiovascular or neurological therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel calcium channel blockers and other dihydropyridine-based active pharmaceutical ingredients (APIs).
• Cardiovascular Drug Research: Used in R&D for developing new antihypertensive and antianginal medications targeting L-type calcium channels.
• Neurological Drug Development: Investigated as a precursor for potential neuroprotective agents or treatments for neurodegenerative diseases.
• Chemical Biology Probe: Serves as a tool compound for studying ion channel function and structure-activity relationships (SAR) in biological systems.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of specialty pharmaceuticals.
• Reference Standard: Used as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical manufacturing.

Basic Information

Product Name	2,6-Dimethyl-3,5-Bis(2'-Propoxyethoxycarbonyl)-4-(2''-Difluoromethoxyphenyl)-1,4-Dihydropyridine
CAS No.	118790-71-9
Molecular Formula	C30H39F2NO8
Molecular Weight	579.64 g/mol
Synonyms	4-(2-Difluoromethoxyphenyl)-2,6-dimethyl-3,5-bis(2-propoxyethoxycarbonyl)-1,4-dihydropyridine; 1,4-Dihydropyridine-3,5-dicarboxylic acid, 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-, 3,5-bis[2-(propoxy)ethyl] ester; Difluoromethoxyphenyl Dihydropyridine Derivative; CAS 118790-71-9; DFMP-DHP; Propoxyethoxycarbonyl DHP Intermediate
EINECS	Contact for details

Quality Control

Our 2,6-Dimethyl-3,5-Bis(2'-Propoxyethoxycarbonyl)-4-(2''-Difluoromethoxyphenyl)-1,4-Dihydropyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.