Description

Vatanidipine is a potent and selective dihydropyridine calcium channel blocker. This compound is of significant interest in pharmaceutical research and development for its cardiovascular activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new antihypertensive and antianginal agents. Vatanidipine CAS NO 116308-55-5 represents a high-purity research chemical for advanced pharmacological studies.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Active Pharmaceutical Ingredient (API) Research: Used as a key intermediate or target molecule in the R&D of new calcium channel blocker medications.
• Biochemical & Pharmacological Studies: Employed in in vitro and in vivo studies to investigate mechanisms of vascular smooth muscle relaxation and cardiac effects.
• Metabolite Identification & Profiling: Acts as a parent compound in studies to identify and characterize its metabolic pathways.
• Formulation Development: Used in pre-formulation studies to assess compatibility, stability, and solubility for potential dosage forms.

Basic Information

Product Name	Vatanidipine
CAS No.	116308-55-5
Molecular Formula	C₂₆H₂₈N₂O₇
Molecular Weight	480.51 g/mol
Synonyms	Vatanidipine; CCB-147; 3-O-(2-Acetoxyethyl) 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic Acid 3-[2-(Acetyloxy)ethyl] 5-Methyl Ester; 3-(2-Acetoxyethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
EINECS	Contact for details

Quality Control

Our Vatanidipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.