Description

Olradipine is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) belonging to the dihydropyridine class of calcium channel blockers. This compound is critical for the research, development, and production of cardiovascular medications targeting hypertension and angina. It is primarily utilized by pharmaceutical manufacturers, R&D laboratories, and fine chemical synthesis facilities. Our supply is characterized by stringent quality control, ensuring reliability for critical pharmaceutical applications.

Application

• Pharmaceutical API Synthesis: Key intermediate in the production of advanced calcium channel blocker drugs.
• Cardiovascular Research: Used as a reference standard and active compound in preclinical and clinical studies for hypertension.
• Fine Chemical Manufacturing: Serves as a building block for synthesizing more complex dihydropyridine derivatives.
• Analytical Standard: Provides a high-purity benchmark for quality control and method validation in analytical laboratories.
• Formulation Development: Employed in the development of stable and effective dosage forms, such as tablets or capsules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production.

Basic Information

Product Name	Olradipine
CAS No.	115972-78-6
Molecular Formula	C19H20N2O5
Molecular Weight	356.37 g/mol
Synonyms	Olradipine; 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-(2-methoxyethyl) 5-methyl ester; (±)-Olradipine; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(2-methoxyethyl) 5-methyl ester; YM-09730-5; YM 09730-5
EINECS	Contact for details

Quality Control

Our Olradipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets exacting standards for pharmaceutical use. Certificates of Analysis (COA) are provided with every shipment, detailing all test results against agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.