Description

Ceronapril CAS NO 111223-26-8 is a high-purity active pharmaceutical ingredient (API) belonging to the class of angiotensin-converting enzyme (ACE) inhibitors. This compound is critical for the research and development of novel cardiovascular therapeutics, offering a pathway to new treatments for hypertension and heart failure. It is primarily required by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.
• Drug Discovery & Development: Used as a key intermediate or lead compound in the synthesis and biological evaluation of new ACE inhibitor candidates.
• Process Chemistry Research: Employed in the development and optimization of scalable synthetic routes for the production of related pharmaceutical compounds.
• Metabolite Studies: Utilized in pharmacokinetic and metabolic pathway research to understand the drug's behavior in biological systems.
• Academic Research: A vital tool for biochemical and pharmacological studies investigating the renin-angiotensin system.

Basic Information

Product Name	Ceronapril
CAS No.	111223-26-8
Molecular Formula	C20H28N2O5
Molecular Weight	376.45 g/mol
Synonyms	Ceronapril; (S)-1-[(S)-3-Benzoyl-2-(tert-butoxycarbonyl)propionyl]pyrrolidine-2-carboxylic Acid; Ceranapril; SQ 29852; (2S)-1-[(2S)-3-Benzoyl-2-[(2-methylpropan-2-yl)oxycarbonyl]propanoyl]pyrrolidine-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our Ceronapril is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research materials. A detailed Certificate of Analysis (COA) providing results for assay, related substances, and residual solvents is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.