Description

Capozide CAS NO 110075-07-5 is a fixed-dose combination pharmaceutical active ingredient primarily used in antihypertensive therapy. This compound is significant for its dual-action mechanism, which offers a synergistic effect for managing blood pressure. It is essential for pharmaceutical manufacturers developing cardiovascular medications, particularly for patients requiring combination therapy. The product is supplied under stringent quality controls to ensure consistency and efficacy in final drug formulations.

Application

• Hypertension Treatment: Primary use in the formulation of oral tablets for the management of high blood pressure.
• Cardiovascular Drug Manufacturing: Serves as a key active pharmaceutical ingredient (API) in the production of combination antihypertensive drugs.
• Clinical Research: Used in preclinical and clinical studies for developing new cardiovascular therapeutic regimens.
• Generic Pharmaceutical Production: A critical component for manufacturers producing generic versions of established combination therapies.
• Dosage Form Development: Utilized in R&D for creating various solid oral dosage forms like tablets and capsules.

Basic Information

Product Name	Capozide
CAS No.	110075-07-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Captopril and Hydrochlorothiazide Combination; Capoten-HCTZ; Captopril-HCTZ; Lopirin-H; Acepril-D; Tensobon; Antihypertensive Combination API; Fixed-Dose Antihypertensive Agent
EINECS	Contact for details

Quality Control

Our Capozide is manufactured and tested under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure it meets the required specifications for pharmaceutical use, including identity, purity, and potency. We provide full traceability and support regulatory submissions. Certificates of Analysis (COA) documenting compliance with relevant pharmacopeial standards (such as USP/EP) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (Captopril)	98.0% - 102.0%
Assay (Hydrochlorothiazide)	98.0% - 102.0%
Related Substances (HPLC)	Meets pharmacopeial limits
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.