Description

Utibaprilat is a potent and selective active pharmaceutical ingredient (API) belonging to the class of angiotensin-converting enzyme (ACE) inhibitors. This compound is of significant commercial and research interest for its role as a key intermediate in the synthesis of advanced cardiovascular therapeutics. It is primarily utilized by pharmaceutical manufacturers and R&D organizations focused on developing and producing innovative antihypertensive and heart failure medications. Our supply ensures high purity and consistent quality to meet the stringent demands of global pharmaceutical production.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of finished ACE inhibitor drug formulations.
• Active Pharmaceutical Ingredient (API): Serves as the core bioactive component in antihypertensive medications.
• Research & Development: Used in biochemical and pharmacological studies to investigate ACE inhibition mechanisms and structure-activity relationships.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Preclinical Studies: Utilized in animal model research for evaluating the efficacy and safety profiles of new cardiovascular drug candidates.

Basic Information

Product Name	Utibaprilat
CAS No.	109683-79-6
Molecular Formula	C20H28N2O5
Molecular Weight	376.45 g/mol
Synonyms	Utibaprilat; (S)-1-[(S)-3-Benzoyl-2-(tert-butoxycarbonyl)propionyl]pyrrolidine-2-carboxylic Acid; SQ 32,925; SQ-32925; SQ32925; 2-Pyrrolidinecarboxylic acid, 1-[(1S)-3-benzoyl-2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxopropyl]-, (2S)-; Benazeprilat Impurity C; ACE Inhibitor Intermediate.
EINECS	Contact for details

Quality Control

Our Utibaprilat is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and spectroscopy. A Certificate of Analysis (COA) is provided with every shipment, detailing the specific results for that lot. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.