Description

Utibapril CAS NO 109683-61-6 is a high-purity pharmaceutical intermediate and active ingredient belonging to the class of angiotensin-converting enzyme (ACE) inhibitors. This compound is critical for the research, development, and production of cardiovascular medications, offering a key building block for advanced therapeutic formulations. It is primarily required by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers serving the global life sciences sector.

Application

• Primary active pharmaceutical ingredient (API) in the synthesis of antihypertensive drugs.
• Key intermediate for advanced pharmaceutical research into next-generation ACE inhibitors.
• Reference standard for analytical method development and quality control in pharmaceutical manufacturing.
• Building block in medicinal chemistry for creating novel therapeutic compounds targeting the renin-angiotensin system.
• Used in pharmacokinetic and pharmacodynamic studies within preclinical and clinical research.
• Essential material for process development and scale-up in GMP-compliant production facilities.

Basic Information

Product Name	Utibapril
CAS No.	109683-61-6
Molecular Formula	C20H28N2O5S
Molecular Weight	408.51 g/mol
Synonyms	Utibapril; (S)-1-[(S)-3-Mercapto-2-methylpropanoyl]pyrrolidine-2-carboxylic acid (3S)-2-oxo-1,3-thiazolidin-3-yl ester; SQ 29852; FPL 63547; 1-[(2S)-3-Mercapto-2-methyl-1-oxopropyl]-L-proline (3S)-2-oxo-3-thiazolidinyl ester; L-Proline, 1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-, (3S)-2-oxo-3-thiazolidinyl ester
EINECS	Contact for details

Quality Control

Our Utibapril is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, IR for identification, and tests for residual solvents and moisture content. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support audits and can provide documentation for GMP and ICH Q7 compliance upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.