Description

Teludipine Hydrochloride is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) of significant commercial and research interest. Its primary value lies in its role as a key building block for the synthesis of advanced calcium channel blockers and other cardiovascular agents. This compound is essential for pharmaceutical R&D laboratories, API manufacturers, and fine chemical suppliers serving the global life sciences sector. Teludipine Hydrochloride CAS NO 108700-03-4 is recognized for its specific pharmacological activity profile.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel dihydropyridine-class calcium channel blockers.
• Active Pharmaceutical Ingredient (API) Development: Serves as the core active moiety in the formulation of cardiovascular drugs under clinical and preclinical investigation.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies targeting L-type calcium channels.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke pharmaceutical compounds.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry programs and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Teludipine Hydrochloride
CAS No.	108700-03-4
Molecular Formula	C19H21N3O2 • HCl
Molecular Weight	359.85 g/mol (for hydrochloride salt)
Synonyms	Teludipine HCl; Teludipine Hydrochloride; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-(1-methylethyl) ester, hydrochloride; Isopropyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate hydrochloride; CAS 108700-03-4
EINECS	Contact for details

Quality Control

Our Teludipine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. We provide full traceability and support regulatory filings. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.