Description

Naltiazem CAS NO 108383-95-5 is a high-purity pharmaceutical intermediate and research chemical. This compound is of significant interest for its role in the synthesis and development of novel therapeutic agents, particularly within the field of cardiovascular and neurological research. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in advanced medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for cardiovascular and neurological applications.
• Research & Development: Used as a reference standard and starting material in medicinal chemistry for drug discovery programs.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex molecules for biological evaluation.
• Academic Studies: Serves as a model compound in university and institutional research for studying specific biochemical pathways and receptor interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	Naltiazem
CAS No.	108383-95-5
Molecular Formula	C26H33N3O6S
Molecular Weight	515.62 g/mol
Synonyms	Naltiazem; 1,5-Benzothiazepine-4(5H)-one, 3-(acetyloxy)-8-chloro-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, (2S,3S)-; (2S,3S)-3-(Acetyloxy)-8-chloro-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; Lercanidipine Impurity; Lercanidipine Related Compound
EINECS	Contact for details

Quality Control

Our Naltiazem is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical testing, including HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.