Description

3,5-Pyridinedicarboxylic Acid, 1,4-Dihydro-2,6-Dimethyl-4-(3-Nitrophenyl)-, Methyl 1-(Phenylmethyl)-3-Pyrrolidinyl Ester, [S-(R*,S*)]- is a high-purity, stereochemically defined pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in developing and producing advanced therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the multi-step synthesis of novel drug candidates, particularly in cardiovascular and neurological research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the construction of complex molecular frameworks for potential APIs targeting specific biological pathways.
• Asymmetric Synthesis: Employed as a reagent or intermediate in stereoselective chemical reactions to introduce defined chirality into target molecules.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for method development and exploration of new chemical entities.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Fine Chemical Production: Acts as a specialized intermediate for the custom synthesis of other high-value, complex organic compounds.

Basic Information

Item	Details
Product Name	3,5-Pyridinedicarboxylic Acid, 1,4-Dihydro-2,6-Dimethyl-4-(3-Nitrophenyl)-, Methyl 1-(Phenylmethyl)-3-Pyrrolidinyl Ester, [S-(R*,S*)]-
CAS No.	104713-77-1
Molecular Formula	C27H28N2O6
Molecular Weight	476.53 g/mol
Synonyms	1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 1-(phenylmethyl)-3-pyrrolidinyl ester [S-(R*,S*)]-; Methyl 1-benzyl-3-pyrrolidinyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate; (3S,5R)-Methyl 1-benzyl-5-(1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate)pyrrolidine-3-carboxylate; A stereoisomer of Nifedipine derivative; Benzylpyrrolidine nifedipine analog.
EINECS	Contact for details

Quality Control

Our 3,5-Pyridinedicarboxylic Acid, 1,4-Dihydro-2,6-Dimethyl-4-(3-Nitrophenyl)-, Methyl 1-(Phenylmethyl)-3-Pyrrolidinyl Ester, [S-(R*,S*)]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed when not in use. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.