Description

Elnadipine is a high-purity dihydropyridine calcium channel blocker used in pharmaceutical research and development. This compound is critical for studying cardiovascular pharmacology and developing new therapeutic agents for hypertension and angina. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in drug discovery and preclinical studies. Our supply ensures consistent quality and reliable availability for critical R&D and manufacturing processes.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: Used in the synthesis and scale-up production of finished dosage forms.
• Biomedical Research: A key tool for in vitro and in vivo studies investigating calcium channel modulation, vascular smooth muscle relaxation, and cardiac electrophysiology.
• Drug Discovery & Development: Employed in high-throughput screening (HTS), structure-activity relationship (SAR) studies, and lead optimization programs.
• Analytical Testing: Used to calibrate equipment and validate analytical methods such as HPLC, LC-MS, and NMR in quality control laboratories.

Basic Information

Product Name	Elnadipine
CAS No.	103946-15-2
Molecular Formula	C28H31N3O6
Molecular Weight	505.57 g/mol
Synonyms	Elnadipine; (±)-Elnadipine; 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-(N-benzyl-N-methylamino)]ethyl ester 5-methyl ester; BAY e 5009; BAY-e-5009; BAYe5009
EINECS	Contact for details

Quality Control

Our Elnadipine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research materials. A detailed Certificate of Analysis (COA) providing results for assay, related substances, residual solvents, and other critical parameters is supplied with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.