Description

Mebudipine CAS NO 103521-70-6 is a potent dihydropyridine-class calcium channel blocker primarily used in pharmaceutical research and development. This compound is of significant interest for its potential cardiovascular applications, acting as a vasodilator to lower blood pressure. It is a critical intermediate and active pharmaceutical ingredient (API) for researchers and manufacturers in the pharmaceutical and life science sectors.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced cardiovascular drug candidates.
• Research Chemical: Used in preclinical and biochemical research to study calcium channel mechanisms and vascular physiology.
• Active Pharmaceutical Ingredient (API): Employed in the formulation development of antihypertensive and antianginal medications.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.
• Pharmacological Studies: Applied in in-vitro and in-vivo studies to investigate its efficacy, pharmacokinetics, and safety profile.

Basic Information

Product Name	Mebudipine
CAS No.	103521-70-6
Molecular Formula	C20H24N2O6
Molecular Weight	388.42 g/mol
Synonyms	Mebudipine; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-(1-methylethyl) ester; Isopropyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate; BAY e 5009; CAS 103521-70-6
EINECS	Contact for details

Quality Control

Our Mebudipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) documenting full specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.