Description

Calmidazolium Chloride is a potent and selective inhibitor of the calcium-binding protein calmodulin, playing a critical role in modulating intracellular calcium signaling pathways. This high-purity compound is essential for researchers and developers in life sciences, enabling precise biochemical and pharmacological studies. It is primarily utilized in pharmaceutical R&D, biochemical research, and as a key reference standard in analytical laboratories.

Application

• Biochemical Research: As a selective calmodulin antagonist for studying calcium-mediated signal transduction, enzyme regulation, and cellular processes.
• Pharmaceutical Development: Serves as a crucial pharmacological tool and reference standard in the discovery and validation of novel therapeutic agents targeting calmodulin-dependent pathways.
• Cell Biology Studies: Used to investigate the role of calmodulin in cell cycle progression, cytoskeletal organization, and neurotransmitter release.
• Diagnostic Reagent Manufacturing: Employed in the formulation of specialized assay kits and diagnostic reagents for research and clinical analysis.
• Academic Research: A fundamental reagent in university and institutional labs for graduate and post-doctoral research projects in pharmacology and molecular biology.

Basic Information

Product Name	Calmidazolium Chloride
CAS No.	94724-12-6
Molecular Formula	C20H19ClN4
Molecular Weight	350.85 g/mol
Synonyms	Calmidazolium; R 24571; 1-[Bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazolium Chloride; R-24571; Calmidazolium Chloride (R24571); R24571 Hydrochloride; Compound R24571; N-[Bis(4-chlorophenyl)methyl]-N'-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazolium Chloride
EINECS	Contact for details

Quality Control

Our Calmidazolium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.