Description

[Ptyr1146][Ptyr1150][Ptyr1151]Insulin Receptor 1142-1153 is a synthetic peptide fragment corresponding to a specific sequence of the human insulin receptor, a critical component in cellular signaling pathways. This high-purity peptide is essential for advanced biochemical research, enabling the study of insulin action, receptor-ligand interactions, and the development of novel therapeutic strategies. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on metabolic disorders and diabetes.

Application

• Biochemical Research: Used as a key reagent in studying insulin receptor structure, function, and tyrosine kinase activity.
• Antibody Production & Epitope Mapping: Serves as an immunogen or antigen for generating and characterizing antibodies specific to the insulin receptor.
• Signal Transduction Studies: Employed in competitive binding assays and experiments to elucidate downstream signaling cascades initiated by insulin.
• Drug Discovery & Screening: Acts as a target molecule in high-throughput screening (HTS) platforms to identify potential insulin mimetics or receptor modulators.
• Diagnostic Development: Used in the development of immunoassays and biosensors for detecting insulin receptor-related biomarkers.
• Academic & Pharmaceutical R&D: A fundamental tool for basic science and pre-clinical research into diabetes, insulin resistance, and related metabolic syndromes.

Basic Information

Product Name	[Ptyr1146][Ptyr1150][Ptyr1151]Insulin Receptor 1142-1153
CAS No.	141171-54-2
Molecular Formula	C72H106N20O21
Molecular Weight	1563.7 g/mol
Synonyms	Insulin Receptor (1142-1153); Insulin Receptor Peptide (1142-1153); IR (1142-1153); H2N-Tyr-Arg-Asp-Ile-Tyr-Glu-Thr-Asp-Tyr-Tyr-Arg-Lys-OH; Insulin Receptor Tyrosine Kinase Domain Peptide; Insulin Receptor Substrate Peptide; PTYR1146,1150,1151; IR 1142-1153
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and analyzed under stringent quality systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive characterization including HPLC for purity determination and Mass Spectrometry (MS) for identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all analytical results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Composition	Within ± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.