Description

Cdc2(6-20)Nh2 CAS NO 136688-17-0 is a synthetic peptide fragment derived from the cell division control protein 2 (Cdc2), a key regulatory kinase in the cell cycle. This high-purity biochemical reagent is essential for fundamental life science research, particularly in the study of cell cycle progression, protein-protein interactions, and kinase signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies engaged in oncology, molecular biology, and proteomics.

Application

• Biochemical Research: Used as a substrate or inhibitor in kinase activity assays to study Cdc2/cyclin B complex function.
• Antibody Production: Serves as a specific antigen for generating and screening monoclonal or polyclonal antibodies targeting the Cdc2 kinase domain.
• Signal Transduction Studies: Employed in pull-down assays, co-immunoprecipitation, and other techniques to map protein interaction networks within the cell cycle machinery.
• Diagnostic Development: Potential use in developing ELISA or other immunoassays for detecting biomarkers related to cell cycle dysregulation.
• Cell Biology & Proteomics: Used in mass spectrometry studies for post-translational modification analysis and functional proteomics of the mitotic apparatus.

Basic Information

Product Name	Cdc2(6-20)Nh2
CAS No.	136688-17-0
Molecular Formula	C71H121N23O20
Molecular Weight	1560.86 g/mol
Synonyms	Cdc2 (6-20) amide; p34cdc2 (6-20) peptide; Cyclin-dependent kinase 1 (CDK1) fragment (6-20); Cell division control protein 2 homolog (6-20)NH2; CDK1(6-20)NH2; Cdc2 kinase peptide (6-20); H-Gly-Glu-Glu-Gly-Thr-Tyr-Gly-Val-Val-Tyr-Lys-Met-Pro-His-Lys-Arg-Arg-Lys-NH2; p34cdc2/cyclin B substrate peptide
EINECS	Contact for details

Quality Control

Our Cdc2(6-20)Nh2 is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical characterization, including reverse-phase HPLC for purity assessment and mass spectrometry (MS) for identity confirmation. Certificates of Analysis (COA) detailing purity, net peptide content, and analytical data are provided with every shipment to support your critical research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake. Aliquot into single-use quantities to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95%
Net Peptide Content	≥ 70%
Amino Acid Analysis	Within ± 10% of theoretical
Solubility	Soluble in water or aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.