Description

Caged-Ins(145)P3 P4 is a specialized caged compound, a photolabile precursor designed for controlled release applications. Its core value lies in providing researchers with precise temporal and spatial control over the activation of biological molecules or signaling agents using light. This product is essential for advanced life science research, particularly in neuroscience and cell biology, where it enables the study of dynamic cellular processes. The compound is identified by CAS No. 119147-20-5.

Application

• Photochemical Release Studies: Used as a caging group for nucleotides (e.g., ATP, GTP, cAMP), neurotransmitters (e.g., glutamate, GABA), or second messengers to study rapid physiological events.
• Neuroscience Research: Enables the precise, localized uncaging of neuroactive compounds to map neural circuits and investigate synaptic transmission.
• Cell Signaling Pathway Analysis: Facilitates the controlled activation of specific intracellular messengers to dissect complex signaling cascades with high temporal resolution.
• Developmental Biology: Applied in studies of morphogen gradient formation and tissue patterning through light-directed release of signaling molecules.
• Drug Discovery Platforms: Serves as a tool for developing and validating light-activated prodrugs or therapeutic agents.
• Biophysical Probes: Incorporated into fluorescent or spectroscopic probes for studying protein dynamics and conformational changes.

Basic Information

Product Name	Caged-Ins(145)P3 P4
CAS No.	119147-20-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Caged Inositol Polyphosphate; 1-(2-Nitrophenyl)ethyl-caged Ins(1,4,5)P3/P4; Photolabile InsP3/InsP4 derivative; NPECaged-Ins(1,4,5)P3/P4; Light-sensitive inositol phosphate precursor; "Caged" IP3/IP4; NPE-caged Insp(145)P3/P4
EINECS	Contact for details

Quality Control

Every batch of Caged-Ins(145)P3 P4 is produced and tested under stringent conditions to ensure the high purity and performance required for sensitive research applications. Our quality assurance includes rigorous analytical testing such as HPLC for purity and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee traceability and compliance with your research standards.

Storage

Preserve in a tightly closed container, protected from all light exposure. Store in a cool, dry place at -20°C or below for long-term stability. Due to its hygroscopic (moisture-sensitive) nature, the container should be equilibrated to room temperature before opening to prevent condensation. For optimal performance, aliquots are recommended to minimize freeze-thaw cycles and repeated exposure to air.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in aqueous buffer systems

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.