Description

Dopamine D4 Receptor CAS NO 137750-34-6 is a high-purity chemical reference standard and research compound. This compound is a selective antagonist for the dopamine D4 receptor subtype, a key target in neuropharmacological research. It is essential for researchers and developers in the pharmaceutical and biotechnology sectors investigating central nervous system disorders, receptor pharmacology, and drug discovery programs.

Application

• Pharmacological Research: Used as a selective tool compound for studying the function and distribution of dopamine D4 receptors in the brain.
• Drug Discovery & Development: Serves as a critical reference standard and lead compound in the design of novel therapeutics for neuropsychiatric conditions.
• Biochemical Assays: Employed in high-throughput screening (HTS), receptor binding assays, and functional studies to evaluate compound efficacy and selectivity.
• Academic & Institutional Research: Supports fundamental neuroscience research in universities and government laboratories.
• In Vitro Diagnostics: Used in the development of diagnostic tests and research kits targeting dopaminergic pathways.
• Preclinical Studies: Applied in animal model research to understand behavioral pharmacology and potential treatment mechanisms.

Basic Information

Item	Detail
Product Name	Dopamine D4 Receptor
CAS No.	137750-34-6
Molecular Formula	C19H21N3O2S
Molecular Weight	355.46 g/mol
Synonyms	L-745,870; 3-[(4-(4-Chlorophenyl)piperazin-1-yl)methyl]-1H-pyrrolo[2,3-b]pyridine; L 745870; L745870; (3-((4-(4-Chlorophenyl)piperazin-1-yl)methyl)-1H-pyrrolo[2,3-b]pyridine); Dopamine D4 Receptor Antagonist L-745,870
EINECS	Contact for details

Quality Control

Our Dopamine D4 Receptor is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.