Description

Inositol 1,4,6-Trisphosphate is a high-purity, biologically active inositol phosphate derivative, a key signaling molecule in cellular processes. It is essential for researchers and manufacturers requiring precise biochemical tools to study intracellular calcium mobilization and signal transduction pathways. This compound is primarily utilized in life science research, pharmaceutical development, and as a critical reference standard in analytical laboratories.

Application

• Biochemical Research: A vital tool for studying the phosphoinositide signaling cascade, particularly the InsP3 receptor-mediated release of calcium from intracellular stores.
• Pharmaceutical R&D: Used as a reference standard and active investigational compound in drug discovery programs targeting neurological disorders, cardiovascular diseases, and metabolic conditions.
• Cell Biology Studies: Employed to investigate second messenger functions, hormone action, neurotransmitter release, and cell proliferation mechanisms.
• Diagnostic Development: Serves as a critical component in the development of assays and kits for measuring inositol phosphate levels and related enzyme activities (e.g., phospholipase C).
• Enzymology: Used as a substrate for studying the kinetics and specificity of inositol phosphate kinases and phosphatases.

Basic Information

Product Name	Inositol 1,4,6-Trisphosphate
CAS No.	114418-85-8
Molecular Formula	C6H15O15P3
Molecular Weight	420.10 g/mol
Synonyms	Ins(1,4,6)P3; D-myo-Inositol 1,4,6-trisphosphate; 1,4,6-IP3; Inositol-1,4,6-trisphosphoric acid; myo-Inositol 1,4,6-trisphosphate; 1D-myo-Inositol 1,4,6-trisphosphate; Inositol trisphosphate (1,4,6-); IP3 (1,4,6-)
EINECS	Contact for details

Quality Control

Our Inositol 1,4,6-Trisphosphate is manufactured under strict quality systems to ensure batch-to-batch consistency and high biological activity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Biological Activity	Confirmed by calcium release assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.