Description

4,5-Dimethoxy-2-Nitrobenzyl Cyclic Amp is a specialized, caged derivative of cyclic adenosine monophosphate (cAMP) designed for precise biological research. This compound is critical for researchers who require spatiotemporal control over cAMP signaling pathways in cellular and molecular studies. It is primarily utilized in advanced life science research, including neurobiology, cell signaling, and pharmacology, where controlled release of the second messenger is essential.

Application

• Photolysis-Based Cellular Signaling Studies: Acts as a "caged" compound for the light-triggered, controlled release of cAMP to study rapid signaling events.
• Neuroscience Research: Used to investigate the role of cAMP in neuronal plasticity, synaptic transmission, and memory formation.
• Cardiovascular Research: Employed in studies of cardiac cell function and regulation where cAMP is a key secondary messenger.
• Biochemical Assay Development: Serves as a critical reagent in developing and validating assays for phosphodiesterase (PDE) activity or cAMP detection.
• Cell Biology and Physiology: Facilitates the study of intracellular processes regulated by cAMP, such as gene expression, metabolism, and ion channel modulation.

Basic Information

Product Name	4,5-Dimethoxy-2-Nitrobenzyl Cyclic Amp
CAS No.	92313-25-2
Molecular Formula	C₁₉H₂₂N₆O₉
Molecular Weight	478.41 g/mol
Synonyms	4,5-Dimethoxy-2-nitrobenzyl adenosine 3',5'-cyclic monophosphate; DMNB-caged cAMP; 1-(2-Nitro-4,5-dimethoxyphenyl)ethyl adenosine 3',5'-cyclic monophosphate; caged cAMP, DMNB-; NPE-caged cAMP analog; 4,5-Dimethoxy-2-nitrobenzyl ester of cAMP; Photolabile cAMP derivative; 92313-25-2
EINECS	Contact for details

Quality Control

Our 4,5-Dimethoxy-2-Nitrobenzyl Cyclic Amp is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, ensuring reliable performance in your experimental workflows.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is strictly light-sensitive and hygroscopic; prolonged exposure to light, moisture, or ambient temperatures will lead to decomposition. Aliquot contents to minimize freeze-thaw cycles and exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.